Best-rated hotels in Mesilla for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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We offer thousands of Mesilla hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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All Mesilla hotels
New Mexico >
Mesilla

Welcome to Mesilla

Mesilla, a charming town nestled in the heart of New Mexico, awaits your visit with open arms. Explore its rich history as you stroll through its picturesque streets lined with adobe buildings. Immerse yourself in the vibrant culture, savor authentic Southwestern cuisine, and shop for unique handcrafted treasures. Discover the magic of Mesilla - a truly unforgettable experience awaits. Plan your trip now and experience the allure of this captivating destination.

What our users say about Mesilla hotels

Isleta Resort & Casino (Adults Only)
9.8

Exceptional

us James 13 March 2023
The rooms were modern and stylish, and the staff was always friendly. Being in a quiet area made it even better, especially with the hotel being wheelchair accessible. Overall, it was a really pleasant holiday stay! 🌟
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Ramada By Wyndham Albuquerque Midtown
9.8

Exceptional

us David 27 December 2022
The rooms here are comfortable and have nice bathrooms with tubs.
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Drury Plaza Hotel In Santa Fe
9.8

Exceptional

us Andrew 24 February 2023
The location here is just perfect! It's a stone's throw away from a beautiful adobe church that's filled with art. 🎨
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Inn Of The Governors
9.8

Exceptional

us Mary 29 June 2022
We recently enjoyed a romantic escape and were delighted with the complementary breakfast and happy hour snacks provided at our hotel. The location was perfect for exploring the city and had easy access to many restaurants. We also appreciated the added convenience of on-site parking.
While we enjoyed our stay, we did experience some noise from neighboring rooms. Additionally, the pool was smaller than we expected and became crowded quickly.
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Hotel Santa Fe
9.8

Exceptional

us Allen 12 March 2022
The hotel has great staff and location, I loved it. The rooms with the most comfortable bed and an open balcony, as example. Found in a downtown area.
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Hampton Inn & Suites Albuquerque Airport
9.8

Exceptional

us Derrick 25 February 2023
The hotel provided a shuttle to the airport free of charge, and the staff was very friendly and accommodating. The breakfast had a great variety of options, including a hot breakfast. The location was convenient and within close proximity to the airport and other attractions.
The cancellation policy was strict and inflexible. I had to cancel due to unforeseen circumstances, but was unable to receive any refund or flexibility from the hotel.
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Surestay Hotel By Best Western Albuquerque Midtown
9.6

Good

us Conrad 03 March 2023
Enjoyed my stay at this budget hotel, it was very pleasant for the price. the central location was a great bonus, close to taxis, an industrial area, restaurants, and stores. - the room I booked was clean, remodeled, and had a sofabed available.
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Hotel St Francis
9.8

Exceptional

us Richard 04 December 2022
The breakfast spot here was amazing! We both got delicious meals and the location couldn't be better, just a short walk from Trinity. 🍳
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Eldorado Hotel And Spa
9.8

Exceptional

us Dan 03 October 2021
Exceptional staff and central location. A flat-screen TV with cable channels, a personal safe and a seating area were available in my a double room. All the dishes were great, nevertheless you can visit nearby Agave Restaurant & Lounge. The service here was friendly too. Actually everything was good, you're dope!
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Hilton Santa Fe Buffalo Thunder
9.8

Exceptional

us John 28 January 2022
Perfectly located in a nice area, adequate breakfast, soft bed. It had great attached restaurant. Near the beach that was fantastic.
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